Buruli Ulcer is the third common mycobacterial infection after tuberculosis and HD. It is caused by Mycrobacterium Ulcerans and affects children and people living close to rivers and stagnant bodies of water. TNF started supporting the WHO Global Buruli Ulcer Initiative (GBUI) in 1998. In 2001, TNF and SMHF funded a project on surgical intervention in Ghana, as it was the only effective treatment in the absence of chemotherapy or vaccines. In 2003 and 2004 SMHF funded training programme in Ghana on surgical treatment of Buruli Ulcer with the emphasis on skin grafting. In 2005, this programme has been taken over by TNF-funded WHO programme and will be expanded to other endemic countries. TNF also supported WHO in its production of an educational comic book geared towards children in French and English, as chemotherapy or vaccine have yet to be developed and education remains the best form of prevention.